摘要
目的:研究延胡索Corydalis yanhusuo块茎60%乙醇提取物的生物碱成分。方法:采用多种色谱学方法进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果:从延胡索块茎60%乙醇提取物的氯仿可溶部分分离得到9个生物碱,分别鉴定为7-醛基脱氢海罂粟碱(1),O-甲基南天竹碱(2),(+)-O-甲基球紫堇碱(3),d-紫堇碱(4),四氢黄连碱(5),8-氧黄连碱(6),巴马亭(7),四氢巴马亭(8)和去氢紫堇碱(9)。结论:化合物1为首次从生物样品中获得,首次报道了其核磁数据,化合物3为首次从罂粟科植物中分离得到,化合物6为首次从该植物中分离得到。
Objective： To study the chemical constituents from the 60% ethanol extract of Coo＇dalis yanhusuo. Method： The chemical constituents were separated and purified by various chromatographic techniques, and their structures were elucidated by chem- ical evidence and spectroscopic analysis. Result： Nine alkaloids were obtained and determined as 7-formyldidehydroglaucine （1）, nantenine （2） , （ ＋ ） -O-methylhulbocapnine （3） , d-corydaline （4） , tetrahydrocoptisine （5） , 8-oxocoptisine （6） , palmatine （7） , tetrahydropalmatine （8） , and dehydrbcorydaline （9）, respectively. Conclusion： Compound 1 was obtained from natural products for the first time, and its NMR data were firstly reported. Compound 3 was reported from Papaveraceae for the first time,and compound 6 was firstly reported from Corydalis yanhusuo.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2009年第15期1917-1920,共4页
China Journal of Chinese Materia Medica
关键词
延胡索
化学成分
生物碱
Corydalis yanhusuo
chemical constituents
alkaloids
