摘要
设计并合成了８个硫色（满）酮及其衍生物，其中７个化合物未见文献报道，其结构均经红外光谱、核磁共振、氢谱及元素分析证实．体外抑菌试验表明：８个化合物均有不同程度的抑菌活性．化合物９４０２，９４０３效果最好，有开发前景．
On the basis of the fact that thiochrom(an)ones have antifungal activity, eight derivatives of thiochrom(an)one were designed and synthesized. Seven of them had not been found in literature.The stuctures of these compounds were confirmed by IR,1HNMR and elemental analysis. Preliminary antifungal activity experiments in vitro showed that the eight compounds had some activity against the tested fungi to some extent.Compounds of 9402 and 9403 showed significant activity.
出处
《沈阳药科大学学报》
CAS
CSCD
1998年第3期185-189,共5页
Journal of Shenyang Pharmaceutical University
