摘要
目的研究复发性口腔溃疡(ROU)儿童的T细胞亚群和微量元素在血清中的变化。方法临床随机抽取2～12岁患ROU的儿童及年龄性别相当的健康儿童各25例,采静脉血,用多色流式细胞仪检测T细胞亚群。用VIDE022型原子吸收分光光度仪测定血清锌、铁、铜、镁含量。结果与对照组比较,ROU组T细胞亚群(CD3、CD4、CD4/CD8)水平均降低,差异均有统计学意义(t分别=2.32、5.05、2.21,P均<0.05);ROU组微量元素中的锌、铁水平降低,差异均有统计学意义(t分别=4.27、3.95,P均<0.05),而两组的镁和铜比较,差异均无统计学意义(t分别=0.25、1.93,P均>0.05)。结论T细胞亚群、锌和铁降低可能与儿童复发口腔溃疡的发生有关。
Objective To study the blood serum diversification of T cells subpopulation, and trace elements in children suffered from recurrent oral ulcer （ROU）. Method Twenty five children with ROU （aged 2-12 years old） and 25 health children （aged 2-12 years old） were involved in the study. T cells subpopulations were tested by haemospasia and flow cytometry. The content of trace elements in serum was treated by atomic absorption spectraluminosity rite. Results The levels of CD3, CD4, CD4/CD8 and the contents of Zn and Fe in the children with ROU were lower than those in the health children, the statistic difference were remarkable （t=2.32, 5.05, 2.21, 4.27, 3.95, P〈0.05）. The contents of Mg and Cu had no statistic difference between the two groups （t=0.25,1.93,P〉0.05）. Conclusions The decrease of T cells subpopulation and the contents Zn and Fe may be related to the occurrence of ROU in children.
出处
《全科医学临床与教育》
2009年第4期359-360,363,共3页
Clinical Education of General Practice
关键词
复发性口腔溃疡
T细胞亚群
微量元素
recurrent oral ulcer
T cells subpopulation
trace elements
