摘要
背景与目的：经气管镜超声引导针吸活检术（endobronchial ultrasound—guided transbronchial needle aspiration，EBUS-TBNA）是用于诊断纵隔淋巴结等病变的最新微创检查方法。本研究旨在评价EBUS-TBNA用于纵隔淋巴结定性诊断的价值。方法：2009年4月1日-2009年7月16日之间，共计20例纵隔淋巴结肿大患者接受EBUS-TBNA检查。总结穿刺结果，评价该方法的应用价值。结果：20例患者共穿刺淋巴结37组，穿剌成功率100％，未发生并发症。EBUS-TBNA：险查总体准确率90．00％（其中上皮性癌诊断准确率100％），灵敏度84．62％，特异度100％，阳性预测值100％，阴性预测值77．78％。每组淋巴结平均操作时间为11．9min。20例患者术后住院1～17d，中位住院1d。前3例患者各组平均操作时间为36．25min，后17例患者各组平均操作时间为7．76min，两者差异具有显著性（z=3．247，P=0．001）。结论：EBUS-TBNA检查安全性好，准确率高，是用于纵隔淋巴结定性诊断的较好方法。
Background and purpose： Endobronchial ultrasound-guided transbronchial needle aspiration （EBUS-TBNA） is a new minimally invasive method in the dignosis for mediastinal lymph nodes. This study was to evaluate the diagnostic yield of EBUS-TBNA for mediastinal lymph nodes. Methods： Twenty patients with mediastinal lymph nodes found by CT underwent the dignosis by EBUS-TBNA form April 1st 2009 to July 16th 2009. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of EBUS-TBNA were evaluated. Results： Twenty patients with 37 lymph node groups were studied. Overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of EBUS-TBNA for diagnostic were 84.62%, 100%, 100%, 77.78% and 90.00%, respectively. The diagnostic accuracy for cancer was 100%. The operation time was 11.9min per group in average with no serious complication. The median length of hospital stay was 1 （range from 1 to 17 days） day after operation. There were significant differences in the average operation time between the first three patients and the others （36.25 min vs. 7.76 min; z=3.247, P=0.001）. Conclusion： Endobronchial ultrasoundguided transbronchial needle aspiration proved to be a safe procedure with a high yield for the diagnosis of mediastinal lymph nodes.
出处
《中国癌症杂志》
CAS
CSCD
北大核心
2009年第7期523-527,共5页
China Oncology
关键词
经气管镜超声引导针吸活检术
纵隔淋巴结
诊断
endobronchial ultrasound-guided transbronchial needle aspiration
mediastinal lymph nodes
diagnosis
