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舒芬太尼复合罗哌卡因硬膜外麻醉在剖宫产术中的应用 被引量:39

Application of epidural anesthesia with small-dose of sufentanil combined with ropivacaine for caesarean section
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摘要 目的探讨小剂量舒芬太尼复合罗哌卡因硬膜外麻醉用于剖宫产术的临床效能及安全性。方法选择60例ASAI或Ⅱ级的剖宫产产妇,随机均分为两组。A组给予0.75%罗哌卡因12ml加舒芬太尼20μg(1ml),B组给予0.75%罗哌卡因12ml加生理盐水1ml。术中连续监测呼吸和循环状况,评估麻醉效能,观察围手术期不良反应的发生和新生儿情况。结果A组的感觉阻滞起效时间、平面达T10的时间及达到最高阻滞平面时间均明显短于B组(P<0.01);A组最高阻滞平面明显高于B组(P<0.01);两组不良反应、Apgar评分差异无统计学意义。结论剖宫产手术产妇硬膜外罗哌卡因麻醉复合小剂量舒芬太尼的麻醉效果优于单纯应用罗哌卡因,对新生儿Apgar评分无明显影响。 Objective To investigate the efficacy and safety of small-dose of sufentanil combined with ropivacaine epidural anesthesia for elective caesarean section. Methods Sixty primiparae (ASA I or Ⅱ ) schedualed for selective caesarean section were divided into two groups with 30 cases each. 0. 75% ropivacaine plus sufentanil 20 μg(1 ml) was administrated in group A. Normal saline 1 ml was used in group B instead of sufentanil as in group A. BP, HR and SpO2 were assessed. Sensory and motor blockade, abdominal wall relaxation, Apgar score of the neonates and side effects were recorded. Results The onset time, the time reaching analgesic plane T10 and the highest plane were less in group A than those in group B(P〈0. 01). The highest plane of group A was higher than that of group B(P〈0. 01). There were no significant differences in Bromage score, Apgar score and side effects between two groups. Conclusion Epidural block with ropivacaine 0. 75% plus 20μg sufentanil is better than ropivacaine alone for caesarean section without remarkable adverse effect on Apgar score.
出处 《临床麻醉学杂志》 CAS CSCD 北大核心 2009年第7期594-596,共3页 Journal of Clinical Anesthesiology
关键词 舒芬太尼 罗哌卡因 硬膜外麻醉 剖宫产术 Sufentanil Ropivacaine Epidural anesthesia Caesarean section
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参考文献6

  • 1Cherng CH, Yang CP,Wong CS, et al. Epidural fentanyl speeds the onset of sensory and motor blocks during epidural ropivacaine anesthesia. Anesth Analg, 2005,101 : 1834-1837.
  • 2郑红,张庆,夏智群,王国林.妇科手术病人罗哌卡因混合舒芬太尼硬膜外麻醉的效果[J].中华麻醉学杂志,2005,25(3):232-233. 被引量:21
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二级参考文献6

  • 1Leighton BL, Arkoosh VA, Huffnagle S, et al. The dermatomal spread of epidural bupivacaine with and without prior intrathecal sufentanil. Anesth Analg, 1996,83:526-529.
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  • 6Maves TJ, Gebhart GF. Antinociceptive synergy between intrathecal morphine and lidocaine during visceral and somatic nociception in the rat. Anesthesiology, 1992,76: 91-99.

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