摘要
白色念珠菌等真菌是能够引起人类及动物患病的重要致病菌,测定了白鲜碱对临床22株临床分离氟康唑耐药白色念珠菌的最小抑菌浓度(MIC),采用棋盘式微量稀释试验测定了两药联合应药的分级抑制浓度指数(ractional inhibitory concentration index,FICI)值。结果表明,白鲜碱有较好的抗白色念珠菌活性且与氟康唑有协同作用。
Candida albicans (C. albicans) and other fungi important human and veterinary pathogens. The minimal inhibitory concentration (MIC) of dictamnine alone and in combination with fluconazole (FLC) against clinical 22 clinical Candida albicans were tested, and checkerboard assay was used to analyze the ractional inhibitory concentration index (FICI) of the combination of dictamnine and FLC. The result showed that dictamnine had good antifungal activity alone and in combination with FLC against Candida albicans.
出处
《中国农学通报》
CSCD
北大核心
2009年第16期21-24,共4页
Chinese Agricultural Science Bulletin
基金
国家自然科学基金项目"大肠杆菌超突变子在耐药性发生和转移中的作用"(No.30671586)资助