摘要
目的:回顾性研究散发性戊型病毒性肝炎(戊肝)的临床特点。方法:对138例戊肝患者的临床特点进行回顾性分析,按年龄分为青年组、中年组和老年组,按是否重叠感染其他肝炎病毒分为单纯组和重叠组。分别比较各组的重型肝炎发生率、临床症状、实验室检查和治疗转归。结果:138例戊肝患者中,老年组的重型肝炎发生率(57.6%)明显高于青年组(20.8%)和中年组(39.5%)(P<0.05)。老年组患者症状较重,并发症发生率高于青中年组,血清总胆红素(Tbil)高于青、中年组(P<0.05);重叠组重型肝炎发生率(75.0%)明显高于单纯组(30.2%),重叠组症状较重,Tbil水平较高(P<0.05)。老年组及重叠组患者住院费用较高。结论:戊肝患者以中老年人、男性多见,老年及重叠感染患者症状重,重型肝炎发生率较高,并发症多,预后较差。
Objective： To investigate the clinical features of patients with hepatitis E （HE） retrospectively. Methods： Clinical data of 138 patients with HE were analyzed retrospectively. Patients were divided into the youth, the middle-aged and the aged group according to their age. Patients were then subgrouped into simple infection group and overlapping infection group according to the superinfection of the other hepatitis virus. The incidence of severe hepatitis, clinical symptoms, experimental examination and prognosis were compared. Results： The incidence of severe hepatitis （57. 6%） in the aged group was higher than that in the youth group （20. 8%） and the middleaged group （39. 5%） （P〈0. 05）. Symptoms in aged group were more serious, and incidence of complications and level of total bilirubin （Tbil） were higher than those in the youth and the middle aged group （P〈0. 05）. Incidence of severe hepatitis （75.0%） in overlapping infection group was obviously higher than that in simple infection group （30. 2%）. Symptoms was more serious in overlapping infection gtoup, and level of bilirubin was higher in overlapping infection group （P〈0. 05）. The cost of hospitalization was higher in the aged and overlapping infection group. Conclusions： HE is mostly seen in male and the aged patients. A nigher incidence of severe hepatitis, more complications and poor prognosis were seen in the aged and overlapping infection patients.
出处
《内科急危重症杂志》
2009年第4期188-190,共3页
Journal of Critical Care In Internal Medicine
