摘要
在胰岛素的效价测定方法中，以前一直用生物测定法。本文用ＨＰＬＣ法和小鼠血糖生物测定法进行了多批ＤＮＡ重组人胰岛素（ｒｈ－Ｉｎｓｕｌｉｎ）效价测定，结果表明两法间有良好的相关性，对高纯单组分ｒｈ－Ｉｎｓｕｌｉｎ的效价测定，ＨＰＬＣ法可代替生物测定法。
RP-HPLC assay and mouse blood glucose bioassay were used for the determination of rh-insulin samples potencies.The results correlated well in two methods.The mouse blood glucose bioassay could be replaced by RP-HPLC assay for highly purified rh-insulin.
出处
《药物分析杂志》
CAS
CSCD
北大核心
1998年第4期241-243,共3页
Chinese Journal of Pharmaceutical Analysis
