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一种新的2型糖尿病易感基因:TCF7L2 被引量:4

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作者 马聪 盛宏光
出处 《江苏大学学报(医学版)》 CAS 2009年第4期362-365,共4页 Journal of Jiangsu University:Medicine Edition
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参考文献30

  • 1Grant SF, Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCFTL2) gene confers risk of type 2 diabetes [ J ]. Nat Genet, 2006,38 ( 3 ) : 320 - 323.
  • 2Gudmundsson J, Sulem P, Steinthorsdottir V, et al. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protest against type 2 diabetes [ J ]. Nat Genet ,2007,39 ( 8 ) :977 - 983.
  • 3van de Wetering M,Oosterwegel M, Dooijes D, et al. I- dentification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box[J]. EMBO J,1991,10(1) :123 -132.
  • 4Castrop J,van Norren K, Clevers HA. A gene family of HMG-box transcription factors with homology to TCF-1 [ J ]. Nucleic Acids Res, 1992,20 ( 3 ) :611.
  • 5Duval A, Busson-Leconiat M, Berger R, et al. Assignment of the TCF4 gene (TCF7L2) to human chromosome band 10q25.3 [ J ]. Cytogenet Cell Genet,2000,88 (3) :264 -265.
  • 6Reynisdottir I, Thorleifsson G, Benediktsson R, et al. Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2[ J]. Am J Hum Genet, 2003, 73(2) :323 -335.
  • 7Grant SF,Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes [ J ]. Nat Genet, 2006,38 ( 3 ) : 320 - 323.
  • 8Freathy RM,Weedon MN, Bennett A, et al. Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals[J]. Am J Hum Genet, 2007, 80 (6) :1150 - 1161.
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  • 10Cauchi S, Choquet H, Gutierrez-Aguilar R, et al. Effects of TCF7L2 polymorphisms on obesity in European populations [ J ]. Obesity ( Silver Spring ), 2008, 16 (2) :476 -482.

同被引文献51

  • 1王旭东,丁显平.2型糖尿病相关基因研究进展[J].中国优生与遗传杂志,2006,14(1):4-5. 被引量:4
  • 2沈亚非,徐焱成.高糖高脂膳食和链脲佐菌素诱导2型糖尿病模型的建立[J].实用诊断与治疗杂志,2006,20(9):649-650. 被引量:50
  • 3黄青,高津福,王雅南,张乐,徐菁玲.白细胞介素1受体拮抗剂基因型与糖尿患者群中牙周炎的关系[J].实用口腔医学杂志,2007,23(4):571-574. 被引量:5
  • 4Poeiot F, Molbig J, Wogensen L, et al. A Taql polymirphism in the human interlenkin-1β beta ( IL-1β) gene correlates with IL-1β secretion in vitro [J]. Eur J Clin Inves,1992,22(6) :396-402.
  • 5Grant S F, Thorleifsson G, Reynisdottir L Variant of tran- scriptionfactor7-1ike 2(TCF7L2)gene confers risk of type 2 di- abetes. Nat Genet, 2006, 38: 320-323.
  • 6Christopher J G, Eleftheria Z, Jayne M, et al. Association a- nalysis of 6,736 U. K. subjects provides replication and con- firms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes, 2006, 55: 2640-2644.
  • 7Lyssenko V, Lupi R, Marchetti P, et al. Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest, 2007, 8: 2155-2163.
  • 8Chandak G R, Janipalli C S, Bhaskar S. Common variants in the TCFTL2 gene are strongly associated with type 2 diabetes mellitus in the Indian population. Journal of Clinical Endocri- nology & Metabolism, 2007, 2: 504-510.
  • 9Laura J S, Lori L B, Cristen J W, et al. Association of Tran- scription Factor 7 Like 2 (TCF7L2) Variants With Type 2 Di- abetes in a Finnish Sample. Diabetes, 2006, 55: 2649-2653.
  • 10Hrikoshi M, Hara K, Ito C, et al. A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population. Diabetologia, 2007, 50 : 747-751.

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