摘要
用二乙基三胺五乙酸二酐和二氯磷酸－Ｏ－（１－氧－２，２，６，６－四甲基－４－哌啶醇酯）与多甘醇共缩聚，制得一系列三元共聚物配体及其钆（Ⅲ）配合物．表征了配体和配合物的化学结构，并测试了部分配合物的弛豫效能．
A new series of spin labeled phosphate polyglycol DTPA ester terpolymer ligands and their Gd(Ⅲ) complexes were prepared by terpolymerization of diethylene triamine pentaacetic dianhydride(DTPAA),O (1 oxyl 2,2,6,6 tetramethyl 4 piperidyl) phosphoric acid dichloride with diethylene glycol,triethylene glycol or tetraethylene glycol,and followed by metal complexation. The chemical structures of these ligands and Gd(Ⅲ) complexes were characterized by 1 H NMR,IR,ESR and EA.The longitudinal relaxility of some of these Gd(Ⅲ) complexes were also measured.
出处
《武汉大学学报（自然科学版）》
CSCD
1998年第4期413-416,共4页
Journal of Wuhan University(Natural Science Edition)
基金
波谱与原子分子物理国家重点实验室和教育部生物医用高分子材料开放实验室资助
关键词
三元共聚物
自旋标记
钆配合物
MRI contrast agent, terpolymer, Gd(Ⅲ) complex, nitroxide, relaxivity
