摘要
目的:观察泛福舒治疗小儿反复呼吸道感染(RRI)的疗效。方法:将104例患儿随机分为观察组和对照组各52例,两组患儿在发作期均给予抗感染、吸入皮质激素等常规对症治疗。观察组在此治疗基础上每日晨起空腹口服泛福舒1粒,每月连服10d,停20d,3个月为1个疗程。观察两组患儿疗效、临床指标变化、3个月后血清免疫球蛋白IgA、IgG、IgM、IgE变化及不良反应。结果:观察组疗效明显优于对照组(P﹤0.001),观察组呼吸道感染次数、咳嗽、发热、喘息、抗生素使用、激素使用等时间临床指标均比对照组明显减少(P均﹤0.001),观察组血清免疫球蛋白IgA、IgG均比对照组明显升高(P均﹤0.001)。结论:泛福舒治疗RRI具有良好的预防和治疗作用,提高小儿生活质量,减少医疗费用的经济负担,具有广阔的应用前景。
Objective:To observe the therapeutic effect of Broncho-Vaxom (BV) in treating repeated respiratory tract infection(RRI) in children.Methods:A total of 104 patients with RRI were randomly divided into two pill/d for J0 d groups:observation group (52 eases) and control group(52 eases),Based on symptomatic treatment, observation group took orally BV 1 pill/d for 10 d every month for 3 months while the control group only took routine treatment. The therapeutic effect ,change of clinical index ,serum immunoglobulin level and adverse reaction of two groups were compared.Results:The effecs in observation group were superior to control group (P〈O.O01).The occurrence of RRI, the duration of cough, fever, gasping, antibiotics and hormone used time of observation group were shorter than those of control group(all P〈0.001 ).The levels of serum IgA and IgG in 0.001).Conelusion: Broncho-Vaxom has satisfactory prevention and application. observation group were higher than those of control group (all P〈0.001).Conclusion: Broneho-Vaxom has satisfactory prevention and therapeutical effect in treating children's RRI.It is worthy of application.
出处
《现代医药卫生》
2009年第18期2758-2760,共3页
Journal of Modern Medicine & Health
关键词
泛福舒
呼吸道感染
小儿
Broncho-Vaxom
Respiratory tract infection
Ch/ldren