摘要
目的探讨普外科患者术中低血压早期实施脑保护预防脑水肿的方法及疗效。方法54例术中低血压患者分2组,每组27例。早期脑保护组在患者脑水肿症状出现前给予低温、渗透性利尿剂、激素及镇静剂等脑保护措施,晚期脑保护组在脑水肿出现后实施与早期脑保护组相同的脑保护措施。根据G lasgow昏迷评分标准评定2组疗效。结果早期脑保护组术后发生脑水肿7例(25.9%),死亡3例(11.1%)。晚期脑保护组术后发生脑水肿11例(40.8%),死亡5例(18.6%)。术后第1天、第3天、第5天、第7天G lasgow昏迷评分2组比较差别有统计学意义(P<0.05)。结论早期实施脑保护可有效预防低血压性脑水肿,降低其发生率及病死率。
Objective To investigate the methods and efficacy of the early brain protection to prevent the brain edema with low blood pressure patients of general surgery in operation. Methods Fifty-four patients with intraoperative low blood pressure were divided into two groups, 27 cases in each group. Protective measure such as hypothermia, osmotic diuretics, hormone, tranquillizer and other measures before symptoms of brain edema appeared were given in early brain protection group. The same protective measures after symptoms of brain edema appeared was given in other group. Then the effacay was evaluated by Glasgow standard of narcose scroe. Results In early brain protection group, brain edema occurred in 7 cases （25.9%） after operation, and 3 cases（ 11.1% ） were death. In the other group, brain edema occurred 11 cases（40. 8% ） ,and 5 cases（18.6% ） were death. The scores of Glasgow standard of coma was statistically significant differences at the 1^st day ,the 3^rd day,the 5th day and the 7＆th day between two groups（P 〈 0.05 ）. Condusion The early brain protection can prevent the low blood pressure brain edema and can decrease the death rate and the incidence of brain edema.
出处
《新乡医学院学报》
CAS
2009年第5期470-472,共3页
Journal of Xinxiang Medical University
基金
广东省医学科技研究基金(编号:Wstjj2007111136230197102202253)
广东省科技计划项目(编号:2008B030303063)
关键词
脑保护
低血压
脑水肿
brain protection
low blood pressure
brain edema
