摘要
目的通过观察新诊断2型糖尿病患者分别接受持续性皮下胰岛素输注(CSII)和多次皮下注射胰岛素(MSII)治疗前后,观察CSII和MSII对恢复胰岛素第一时相分泌有无差异。方法新诊断的2型糖尿病患者随机分别接受CSII和MSII治疗,治疗前后均测IVGTT各点胰岛素,并得出AIR。结果CSII组治疗前后AIR有显著性差异(P<0.05);MSII组治疗前后AIR无显著性差异(P>0.05);两组治疗后,AIR有显著性差异(P<0.05)。结论新诊断的2型糖尿病患者短期应用CSII,可以恢复或部分恢复糖刺激的胰岛素第一时相分泌,而MSII无此作用。
Objective To observe the effect of short-term intensified intravenous insulin pump treatment on secretion of insulin at first phase newly diagnosed type 2 diabetic patients. Methods Newly diagnosed type 2 diabetic patients were randomly divided into two groups： CSII and MSII. Before and after the treatment,AIR were calculated. Results Two weeks after the treatment,the levels of AIR were significandy increased （P〈0.05） in CSII group. While the levels of AIR were no significantly different in MSII group （P〉0.05）. After treatment,the level of AIR were significantly increased in CSII group （P〈0.05） than MSII group. Conclusions Short-term intesified intravenous insulin pump treatment can effectively of partly increase the secretion of insulin at first phase in newly diagnosed type 2 diabetic patient.
出处
《中国热带医学》
CAS
2009年第9期1664-1665,共2页
China Tropical Medicine
关键词
2型糖尿病
胰岛素泵
第一时相分泌
Type 2 diabetes
Insulin pump
Secretion at first phase
