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缬沙坦联合氟伐他汀治疗糖尿病肾病的临床观察 被引量:6

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摘要 目的探讨缬沙坦联合氟伐他汀治疗糖尿病肾病(DN)的疗效及机制。方法选择糖尿病肾病80例,随机分为治疗组和对照组各40例,对照组单用缬沙坦治疗,治疗组应用缬沙坦联合氟伐他汀治疗,疗程8周。治疗前后观察血脂(TG、TC)、尿白蛋白排泄率(UAER)及血肌酐(Scr)的变化。结果各组较治疗前下降,治疗组下降优于对照组,差异有统计学意义(P<0.05)。结论采用缬沙坦和氟伐他汀治疗糖尿病肾病具有降血脂、减少尿蛋白排泄、改善肾功能、延缓病情进展的作用。
出处 《中国现代药物应用》 2009年第17期96-97,共2页 Chinese Journal of Modern Drug Application
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