摘要
目的监测146株肠球菌对12种抗菌药物的耐药特点。方法用MicroScan WalkAway40及PC20对肠球菌进行鉴定及药敏试验。结果146株肠球菌对青霉素、氨苄西林的耐药率分别为21.2%和15.8%;对红霉素、四环素和利福平的耐药率分别为93.8%、71.2%和62.3%;对高水平庆大霉素和高水平链霉素的耐药率为58.9%和50.0%;发现万古霉素中介的粪肠球菌和屎肠球菌各1株。结论在肠球菌感染治疗中氨苄西林、青霉素仍然是首选药物,当作用于细胞壁的合成药物与氨基糖苷类联合治疗肠球菌感染时,50%以上不出现协同作用,红霉素、四环素和利福平对肠球菌的敏感率较低。
Objective To investigate the distribution and antimicrobial resistance of Enterococcus. Methods Enterococci identification and drug sensitivity test were performed by Microscan Walkaway 40 and PC 20. Results The resistance rates of 146 enterococci to penicillin and ampicillin were 21.2% , 15.8% , respectively; to erythromycin, tetracycline, rifampicin were 93.8% , 71.2% , 62. 3% , respectively; to high - level gentamicin and streptomycin were 58.9% , 50. 0% ; 1 strain of enterococcus faecalis and 1 strain of enterocoecus faecium intervened by vaneomycin were noted. Conclusion Ampicillin and penicillin remain the first choice in enterococcus infection treatment. More than 50% of enterococci have not synergetic effect when acting on combined cell wall synthetic drugs and aminoglycosides antibiotic. The sensitive rates of erythrocin, tetracycline and rifampicin to enterococci were relatively low.
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第18期1698-1700,共3页
Chinese General Practice
关键词
肠球菌属
抗菌药
抗药性
Enterococcus
Anti -bacterial agents
Drug resistance
