摘要
目的探讨复合芬太尼静脉麻醉对内镜逆行胰胆管造影术(ERCP)后胰腺炎的影响。方法将2003年8月至2009年3月重庆市第三人民医院366例接受ERCP的患者随机分为两组:复合芬太尼静脉麻醉组(183例)和对照组(183例)。静脉麻醉组在ERCP操作过程中予咪达唑仑、丙泊酚和芬太尼进行复合静脉麻醉,对照组未予静脉麻醉。结果复合芬太尼静脉麻醉组ERCP后胰腺炎发生率为16.9%,对照组ERCP后胰腺炎发生率为9.3%,P<0.05,有统计学差异;复合芬太尼静脉麻醉组重症胰腺炎发生率1.6%,对照组重症胰腺炎发生率0.5%,P>0.05,无统计学差异。结论复合芬太尼静脉麻醉可能通过多种途径增加发生ERCP后胰腺炎的危险。
Objective To analyze the effect of intraoperative intravenous analgesia combined fenlanyl on post-endoscopic retrograde eholangiopancreatography pancreatitis （PEP）. Methods 366 patients who received endoscopic retrograde cholangiopancreatography （ERCP） from August 2003 to March 2009 were divided into two groups （the trial group and the control group）.The trial group included 183 patients undergoing intraoperative intravenous analgesia combined fentanyl. The control group included 183 patients not undergoing intraoperative intravenous analgesia. Results The incidence of PEP in the trial group was 16.9%, while the incidence of PEP in the control group was 9.3%, P〈0.05; The incidence of severe acute pancreatitis in the trial group was 1.6%, while the incidence of severe acute pancreatitis in the control group was 0.5%, P〉0.05. Conclusion Intraoperative intravenous analgesia combined fentanyl probably increase the risk for PEP.
出处
《中国医药指南》
2009年第14期8-9,共2页
Guide of China Medicine
关键词
芬太尼
静脉麻醉
内镜逆行胰胆管造影术
胰腺炎
危险因素
Fentanyl
Intraoperative intravenous analgesia
Endoscopic retrograde cholangiopancreatography
Pancreatitis
Risk
