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帕金森病伴发抑郁患者血小板5-羟色胺浓度的对照研究 被引量:14

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摘要 目的了解5-羟色胺(5-HT)在帕金森病(PD)伴发抑郁症状中的作用。方法采用高效液相色谱法,分别测定60例PD患者(伴发抑郁症状31例)和48例正常对照者的血小板5-HT含量。结果51.7%的PD患者伴发抑郁症状,PD组5-HT浓度较正常组显著下降,伴发抑郁组PD患者血小板5-HT浓度较未伴发抑郁组亦显著降低。结论本文研究结果支持5-HT代谢异常在PD患者中起重要作用的理论,纠正血小板5-HT浓度异常可能会促进PD患者神经功能康复。
出处 《中国实用神经疾病杂志》 2009年第17期50-51,共2页 Chinese Journal of Practical Nervous Diseases
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参考文献6

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二级参考文献14

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