摘要
目的探讨彩色多普勒超声评价烟雾病颅骨多点钻孔术手术疗效的应用价值。方法15例烟雾病患者行颅骨多点钻孔术，共钻孔46个。手术后1周、3个月超声检测钻孔处新生血管收缩期峰值流速（PSV）、舒张末期流速（EDV）、搏动指数（PI）、阻力指数（RI），观察新生血管走行、形态并比较术后1周及术后3个月新生血管血流动力学参数变化情况。手术前、手术后1周及术后3个月行单光子计算机体层扫描（SPECT），并将术后1周及术后3个月超声探测新生血管情况与SPECT检查所示脑灌注改善情况进行对照。结果①术后1周20个孔彩色多普勒超声测及新生血管；术后3个月42个孔可测及新生血管。术后3个月新生血管PSV、EDV较术后1周明显增快，新生血管RI在术后1周及术后3个月差异无统计学意义。②术后1周共9例患者超声探测到新生血管，且9例患者临床症状均有不同程度改善，而SPECT检查脑灌注均无改善；术后3个月14例患者超声可测及新生血管，且患者临床症状明显改善，而SPECT检查只有3例患者脑灌注有改善。结论彩色多普勒超声可无创性评价烟雾病颅骨多点钻孑L术的手术疗效。
Objective To evaluate the value of ultrasound in assessing multiple burr-hole operation in patients with moyamoya disease. Methods Multiple burr-hole operation was performed in 15 patients and 46 bur holes were made. Neovascularization was detected one week and three months after operation by ultrasound with 7L probe, the peak systolic velocity （ PSV）, end diastolic （ EDV）, pulsatility index （ PI）, resistence index（RI） of the neovascular were measured. The results of one week and three month were compared. SPECT was performed pre- and postoperative （one week and three month, respectively）. The results of ultrasound and SPECT were compared. Results （1）Ultrasound disclosed neovaseularization at 20 of 46 burr holes one week and rich neovascularization at 42 three month. The values of PSV, EDV of neovascularization were significantly different between one week and three month post-operatively,while PI was no difference. （2）Neovascularization can be detected more early by ultrasound than SPECT, and clinical outcomes more coincidence with ultrasound than SPECT. Conclusions Ultrasonography is a noninvasive method for assessing the effect of multiple burr-hole operation in patients with moyamoya disease.
出处
《中华超声影像学杂志》
CSCD
北大核心
2009年第8期698-701,共4页
Chinese Journal of Ultrasonography
基金
首都医学发展基金重点资助项目（2005-2025）
