摘要
目的总结奎屯地区食管癌的治疗经验。方法回顾性分析600例食管癌患者采用不同治疗手段的相关临床资料。结果食管癌患者600例,其中,上段184例,中段220例,下段196例;通过影像学检查有区域淋巴结转移的患者378例,有远处转移患者151例,未发现淋巴结转移的患者222例;单纯手术组104例,单纯放射治疗组92例,单纯化学治疗组68例,手术后放射治疗组97例,手术后化学治疗组84例,放射治疗加化学治疗组80例,营养支持组75例;随访6个月至3年,1年生存率、3年生存率分别为:单纯手术组80.7%、46.2%;单纯放射治疗组52.2%、28.3%;单纯化学治疗组29.4%、8.8%;手术后放射治疗组79.4%、42.3%;手术后化学治疗组72.6%、29.8%;放射治疗加化学治疗组57.5%、21.3%;营养支持组12.0%、2.6%。结论无淋巴结转移的食管癌患者手术、单纯放射治疗可以取得相同的疗效,但后者生活质量明显提高,有区域淋巴结转移的食管癌患者手术后行辅助放射治疗可以明显提高生存率。
Objective To summary the treatment experiences of esophageal carcinoma in Kuitun area. Methods Retrospective study about related clinical material of the 600 esophageal carcinoma patients, that uses the different treatment method. Results Totally 600 patients were enrolled, among of which, 184 esophageal carcinoma patients in upper thoracic,220 patients in midthoracic,and 196 patients in lower thoracic. By screenage inspection,378 patients had positive region lymph nodes metastase, 151 patients had positive distant place lymph nodes metastase,and 222 patients had no lymph nodes metastase ;Pure surgery group 104 patients, radio- therapy alone group 92 patients, the chemotherapy alone group 68 patients, radiotherapy after the surgery group 97 patients, chemotherapy after the surgery group 84 patients, and 80patients treated by radiotherapy combined with chemotherapy , Nutrition support group 75 patients. Makes a follow - up visit for 6 months to 3 years, the 1 - and 3 -year overall survival rate of pure surgery group was 80.7% ,46.2% ;radiotherapy alone group was 52. 2% ,28.3% ;chemotherapy alone group 29.4% ,8.8% ;radiotherapy after the surgery group 79.4% ,42.3% ; chemotherapy after the surgery group 72.6% ,29.8% ;radiotherapy combined with chemotherapy group 57.5 % 21.3% ;Nutrition support group 12.0% ,2.6% ,respectively. Conclusion The esophageal carcinoma patients that had no lymph nodes metastase, surgery and the pure radiotherapy may obtain the same curative effect, but the latter＇s quality of life distinct enhancement,The patients which had positive region lymph nodes metastase,radio- therapy after the surgery can be possible to raise the survival rate obviously.
出处
《社区医学杂志》
2009年第17期13-14,共2页
Journal Of Community Medicine
基金
吴阶平医学基金会资助课题
卫生部科研基金课题(课题编号WKJ2005-3-006〈49〉320.6750.07049)
关键词
食管癌
手术
放射治疗
化学治疗
Esophageal carcinoma
Surgery
Radiotherapy
Chemotherapy
