摘要
目的评估宫颈冷刀锥切术(cold knife conization,CKC)在宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)Ⅲ诊疗中的临床价值。方法采用自身对照方法,对比分析70例CINⅢ患者阴道镜下多点活检、宫颈锥切术及全子宫切除术的病理检查结果。结果CKC与阴道镜多点活检结果完全符合者有43例(61.43%),11例(15.71%)升级,包括9例早期浸润癌,2例宫颈浸润癌,16例(22.86%)降级。28例CINⅢ行全子宫切除术后残留宫颈病理示CINⅢ1例、CINⅡ4例、CINI 3例,炎症20例。所有病例术后随访,宫颈细胞学检查未见异常。宫颈锥切术主要的并发症是术后出血。结论宫颈锥切术可以提高CINⅢ诊断准确率,预防浸润癌的漏诊,是CINⅢ首选的治疗方法。
Aim To explore the value of diagnosis and treatment of cold knife conization to cervical intraepithelial neoplasia（CKC）Ⅲ.Methods Seventy patients with CIN Ⅲ diagnosed and treated were retrospectively analyzed focusing on the comparative study in pathology between colposcopic multiple biopsies and CKC.Results Of the 70 patients,accordance rate of diagnosis was 61.43%,11 cases（15.71%） upgrades,including 9 cases of early invasive carcinoma and 2 cases of invasive carcinoma,16 cases（22.86%） downgrades.28 cases of CIN Ⅲ after hysterectomy cervical pathology showed residual CINⅢ 1 cases, CINⅡ 4 cases, CINⅠ 3 cases, inflammarion 20 cases. All cases were closely followed up, no cytology abnormality was detected. Postoperative hemorrhage was the main side effect for CKC. Conclusion CKC can inprove the diagnostic accuracy and prenvent the omission of invasive carcinoma for the patient with CIN Ⅲ. CKC is the first choice of treatment for the patient with CIN Ⅲ.
出处
《安徽医药》
CAS
2009年第8期907-908,共2页
Anhui Medical and Pharmaceutical Journal
关键词
宫颈上皮内瘤变
冷刀锥切术
诊断
治疗
cervical intraepithelial neoplasia
cold knife conization
digonosis
treatment
