摘要
目的动态观察雷公藤多甙对人工晶体植入术后眼内炎症反应的影响，估价雷公藤多甙的临床治疗效果及其抗炎作用的机制。方法１２０例老年性白内障随机分为２组，施行白内障囊外摘除及后房型人工晶体植入术。１组为雷公藤多甙治疗组；２组为激素治疗组。术后１、３、７及１４天定量观察前房水混浊、人工晶体表面沉着物和纤维蛋白反应。结果雷公藤多甙治疗组术后第１、３、７及１４天房水混浊、人工晶体表面沉着物和纤维蛋白反应低于激素治疗组（Ｐ＜０．０５）。结论雷公藤多甙能降低人工晶体植入术后眼前节炎症反应，雷公藤多甙治疗优于激素治疗。
Objective The effects of tripterygium wilfordii polyglyco-sidium (TWP) on intraocular inflammatory reaction after extracapsular cataract extraction and intraocular lens (IOL) implantation were studied. Methods 120 cases with senile cataract were divided into two groups: (1)Patients received TWP after IOL implantation; (2) patients received prednisone after IOL implantation.The slit-lamp was used to observe inflammatory cells and fibrinous exudate in the aqueous humor and cellular deposits on IOL on the 1st,3rd,7th and 14th postoperative days.Results The study indicated that on the 1st,3rd,7th and 14th postoperative days the inflammatory cells and fibrinous exudate in the aqueous humor and cellular deposits on IOL were significantly lower in TWP-treated group than that in steroid-treated group (P<0.05).Conclusions TWP is effective in reducing postoperative anterior ocular inflammation after extracapsular cataract extraction and IOL implantation. The TWP is more effective than the steroid in suppressing postoperative intraocular inflammatory reaction.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
1998年第5期332-335,共4页
Chinese Journal of Ophthalmology
