摘要
目的观察拓扑替康联合白介素-2治疗恶性浆膜腔积液近期疗效及耐受性。方法经病理组织学及细胞学检查证实的32例恶性浆膜腔积液病例,均采用经皮中心静脉导管浆膜腔内置入引流,引流干净后腔内灌注拓扑替康及白介素-2。结果浆膜腔积液控制率约84.4%,毒副作用轻。结论拓扑替康联合白介素-2治疗恶性浆膜腔积液近期疗效好,毒副作用轻,耐受性好。
Objective To observe the efficacy and tolerance of the combination of topotecan and interleukin-2 for malignant serous effusion patients. Methods 32 patients histologically and cytologically conformed malignant serous effusion received the treatment of the combination of topoteean and interleukin-2 by thoracic infusion after drainage the effusions by pereutaneous transluminal placement of central venous catheter. Results The disease controlled rate is 84.4% and the toxicities is tolerable. Conclusions The efficacy of the combination of topotecan and interleukin-2 for malignant serous effusion patients is good, adverse effect is wild and torlerable.
出处
《川北医学院学报》
CAS
2009年第5期446-447,共2页
Journal of North Sichuan Medical College
