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超敏C-反应蛋白和白介素-18与冠心病之间的关系

Relationship Between the High Sensitivity C-reactive Protein and Interleukin-18 of the Coronary Heart Disease
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摘要 目的探讨hs-CRP和IL-18与冠心病之间的关系。方法选取60例冠心病病人测定其血清中hs-CRP和IL-18浓度,并与20例正常体检者进行对照。结果冠心病组hs-CRP和IL-18浓度均显著高于对照组(P<0.01)。冠心病病人血清hs-CRP与IL-18水平具有正相关性(r=0.285,P<0.05)。结论hs-CRP和IL-18对冠心病的病变程度有预测价值。 Objective To evaluate the relationship between hs-CRP and IL-18 of the CHD. Methods 60 patients of CHD were randomly recruited,and their concentration of serum hs-CRP and IL-18 were determined, then compared with 20 healthy persons. Results hs-CRP and IL-18 of the CHD were significantly higher than the control group(P〈0.01). The elevation of hs-CRP and IL-18 had a relationship(r=-0.285,P〈 0.05).Conclusion The increase of hs-CRP and IL-18 was regarded as a prediction of the CHD.
作者 董立
出处 《中外医疗》 2009年第25期10-10,12,共2页 China & Foreign Medical Treatment
关键词 冠状病 超敏C-反应蛋白 白介素-18 Coronary heart disease High sensitivity C-reactive protein Interleukin-18
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参考文献2

  • 1Mallat Z,Corbaz A,Scoazec A,et al.Interleukin-18/interleukin- 18 binding protein signaling modulates atherosclerotic lesion development and stability[J].Circ Res,2001,89(7):E41 - 45.
  • 2Von der Thusen JH,Kuiper J,van Berkel TJ,et al.Interleukins in atherosclerosis:molecular pathway sand therapertic potential[J]. Pharmacol Rev,2003,55(1):133- 166.

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