摘要
目的探讨腹腔镜直肠前切除手术对患者生存质量的影响。方法前瞻性非随机对照研究,测定同期接受改良腹腔镜直肠前切除(腔镜组)和开腹直肠前切除手术(开腹组)患者短、中期生存质量评分。结果2007年9月～2008年9月,共63例直肠癌患者入选,其中腔镜组27例,开腹组36例。失访5例,其中腔镜组2例,开腹组3例。两组术前生存质量值比较差异无显著性(P>0.05)。术后2周,患者的生存质量值大幅度下降,开腹组的生存质量评分低于腔镜组(P<0.05)。术后4周,患者的生存质量有所好转,但未达到术前水平(P<0.05),开腹组的生存质量评分仍低于腔镜组(P<0.05)。术后12周,患者的生存质量评分已恢复到术前水平(P>0.05),两组间的比较差异无显著性。术后24个月,两组的生存质量评分均高于术前水平(P<0.05),两组间比较差异也无显著性。结论从生存质量角度,改良的腹腔镜直肠前切除手术较开腹手术有着明显的优势。
[ Objective ] To study the quality of life（QL） in patients who accepted modified laparoscopic anterioresection surgery for rectal cancer. [Methods] It was a prospective control study. The values of QL were compared and analysed between laparoseopie anterio-resection surgery group （laparoscopic group） and open anterio-resection surgery group （open group） before the operations and 2, 4, 12, 24 weeks after. [Results] Sixty-three cases with rectal cancer were selected in this study between September 2007 and September 2008, including 27 in laparoscopic group and 36 in open group. Five cases （ 2 in laparoscopic group and 3 in open group ） could not be followed up. There were no significant differences in the values of QL between both groups before surgery （P 〉0.05）. Two weeks after surgery, the values of QL decreased sharply and the values of QL in open group were lower than those in laparoseopic group （P 〈0.05）. Four weeks after surgery, the values of QL increased a little but did not reach the preoperative levels （P 〈0.05）, and the values of QL in open group were still lower than those in laparoseopic group （P 〈 0.05）. Twelve weeks after surgery, the values of QL reached the pre-operative levels （P 〉0.05） and there were no significant differences in the values of QL between these two groups. Twenty-four weeks after surgery, the values of QL exceeded the pre-operative levels （P 〈0.05） and there were no significant differences between these two groups. [ Conclusion] Modified laparoscopic anterio-reseetion surgery is better than open anterio-resection surgery with the advantage of better quality of life for rectal cancer patients.
出处
《中国内镜杂志》
CSCD
北大核心
2009年第8期815-817,821,共4页
China Journal of Endoscopy
基金
广西科学基金项目(桂科自0728080)
关键词
直肠癌
生存质量
腹腔镜
rectal cancer
laparoscopy
quality of life
