摘要
目的探讨男性早发冠心病急性心肌梗死(PCHDAMI)的危险因素及冠状动脉病变特点。方法将290例冠心病急性心肌梗死(CHDAMI)患者分为3组,男、女PCHDAMI组和男性非PCHDAMI组,收集冠心病危险因素、冠状动脉造影资料进行统计学分析。结果(1)男性PCHDAMI组大量吸烟、饮酒及高3酰甘油(TG)患病比率显著高于女性PCHDAMI组和男性非CHDAMI组(P<0.01,P<0.05),高血压患病比率则显著低于女性PCHDAMI及男性非CHDAMI组(P<0.05)。(2)男性PCHDAMI组高尿酸血症患病率高于女性PCHDAMI组,高低密度脂蛋白胆固醇(LDL-C)患病率低于男性非CHDAMI组(P<0.05)。(3)3组梗死相关的血管均主要为前降支(LAD)。(4)男性PCHDAMI组的单支血管病变高于男性非CHDAMI组(P<0.05)而低于女性PCHDAMI组,多支(≥2支)血管病变则低于男性非CHDAMI组(P<0.05)而高于女性PCHDAMI(P<0.05)。结论大量吸烟、饮酒、高三酰甘油及高尿酸血症是男性PCHDAMI主要的危险因素,男性PCHDAMI组的冠状动脉病变的严重程度低于男性非CHDAMI组而高于女性PCHDAMI。
Objective To investigate the risk factors and features of coronary lesions in male patients with premature coronary heart disease acute myocardial infarction（PCHDAMI）. Methods Two hundred and ninety patients with coronary heart diseaae acut myocardial infarction（CHDAMI） were divided into three groups,male PCHDAMI group, female PCHDAMI, aged male CHDAMI. The risk factors and coronary angiographic changes were analyzed and compared among the groups. Results （1） The rate of heavysmoker,liquor-drinker, and increased TG was significantly higher in male PCHDAMI groups than female PCHDAMI and aged male CHDAMI groups（P〈0.01 or P〈0.05）;the rate of hyperpiesia in male PCHDAMI group was significantly lower than that in female PCHDAMI and aged male CHDAMI groups（P〈0.05）. （2）The rate of hyperuricemia in male PCHDAMI group is higher than female PCHDAMI groups（P〈0.05） ; the rate of LDL-C was lower in male PCHDAMI group than aged male CHDAMI group. （3） The infarction-related artery was mainly LAD in three groups. （4）The rate of single-vessel lesions appeared more in male PCHDAMI group than female PCHDAMI group（P〈0.05） ,and less than aged male CHDAMI group（P〈0.05 ）. The multi-vessel lesions appeared less in male PCHDAMI group than aged male CHDAMI group. But the coronary artery lesions were more severe in male PCHDAMI than in female PCHDAMI（P〈0. 05）. Conclusion Heavy-smoking, liquor-drinking, increased TG and hyperuricemia are important risk factors for male PCHDAMI. The coronary artery lesions were more severe in male PCHDAMI group than female PCHDAMI group,and less than aged male CHDAMI group.
出处
《重庆医学》
CAS
CSCD
北大核心
2009年第18期2339-2341,共3页
Chongqing medicine
