摘要
抗血小板治疗在冠状动脉粥样硬化性心脏病治疗中占有重要地位。盐酸替罗非班是一种新型可逆性非肽类血小板表面糖蛋白Ⅱb/Ⅲa受体拮抗剂,可竞争性抑制纤维蛋白原与血小板糖蛋白ⅡbⅢ/a受体的结合,抑制血小板聚集,延长出血时间,抑制血栓形成。近年来该药广泛应用于冠心病治疗,特别是在急性冠脉综合征以及经皮冠状动脉介入治疗中发挥重要作用,是极具前途的抗血小板药物。
Antiplatelet therapy plays an important role in the treatment of coronary atherosclerotic heart disease. As a kind of patelet glycoprotein Ⅱb/Ⅲa a receptor antagonists, tirofiban hydrochloride can competitive inhibit the combination of fibrinogen and platelet glycoprotein Ⅱb/Ⅲa a receptor,and prolong bleeding time,reduce thrombosis. It Is a very promising anti-platelet drug widely used in the treatment of coronary heart disease, especially in acute coronary syndromes and percutaneous coronary intervention in recent years.
出处
《医学综述》
2009年第18期2791-2793,共3页
Medical Recapitulate
