摘要
目的观察应用国内外两种方法行宫颈液基细胞学检查结果的一致性。方法选取602例符合条件的对象采用国内外两种液基细胞学制片方法,进行宫颈液基细胞学检查。细胞学诊断采用TBS分级系统。阳性诊断包括意义不明的不典型鳞状细胞(ASC-US)。细胞学诊断阳性者,全部在阴道镜下取活组织检查,所有检查均在双盲下进行。结果利用国内外两种液基细胞学制片方法,阳性检出率分别为14.62%、15.45%,与组织病理学对照结果显示,鳞状上皮内高度以上病变(>HSIL)均为83.13%(5/6);鳞状上皮低度病变(LSIL)分别为73.1%(19/26)、74.1%(20/27),差异无统计学意义(P>0.05)。结论利用国内外两种液基细胞学制片方法检查,结果有较好的一致性,应用国内液基细胞学制片方法检查,成本较低,能够满足临床诊断的要求。
Objective To compare the concordance of two liquid based cytology materials homemade and imported used in cervical cytological tests. Methods 602 patients were selected to have cervical liquid based cytological test by using twomaterials homemade and imported at the same time. The cytological diagnosis criterionwas TBS taxonomy. All LCT liquid based cytologic test ~atypical squamous cells of undetermined sign ASC US was considered aspositive results, whichwillhave biopsy in colposcopy. All tests were conducted double blind. Results The detected rate of LCT≥ ASCUS examined by homemade and importedmaterialswere 14. 62 % （88/602） and 15.45 % （93/602） respectively. The histopathological resultswere showed that the concordance rate of LCT≥ HSIL were both 83.3 % （5/6）, and LCT--LSIL were 73.1% （19/26） and 74.1%（20/27）, respectively, which showed no significant difference （P〉0.05）. Conclusion It appears good concordance between homemadematerials and imported ones in cervical cytological tests. Homemadematerial is more suitable to be developed in grass root hospitals because of its cheapness.
出处
《西部医学》
2009年第9期1524-1526,共3页
Medical Journal of West China
关键词
液基细胞学检查
方法评价
对比研究
Liquid-based cytological tests
Evaluation method
Comparative study
