期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

适形放射治疗联合单药健择治疗晚期胰腺癌的临床观察 被引量：2

下载PDF
导出
摘要 ①目的评价三维适形放疗联合单药健择化疗治疗晚期胰腺癌的近期疗效及临床受益反应。②方法30例晚期不能手术胰腺癌患者给予适形放疗,2Gy/次,5次/周,总剂量50～60Gy;放疗加用单药健择化疗1000mg/m^2,第1、8天,每4周1次,放疗结束后根据患者一般情况,继续行上述方案化疗,共化疗周期4～6个周期。③结果25例患者完成治疗,82.4%患者疼痛明显缓解,临床受益反应有效率80%;放疗后2个月复查CT,肿瘤缩小>25%者76.5%;1、2年生存率分别为40%和24%。④结论适形放射治疗联合单药健择,是晚期胰腺癌较好的治疗方式。
作者 袁蕾蕾 聂学诚 赵聪 国桂松
机构地区 山东省济宁市第一人民医院肿瘤科
出处 《华北煤炭医学院学报》 2009年第5期626-627,共2页 Journal of North China Coal Medical College
关键词 胰腺癌 放射疗法 健择 临床受益反应
分类号 R735.9 [医药卫生—肿瘤]
  • 相关文献

参考文献8

  • 1Jemal A, Siegel A, Ward E, et al. Cancer statistics 2008 [ J ]. CA Cancer J Clin,2008,58:71.
  • 2Burris H A,Moore M J,Andersen J,et al. Improvements in survival and clinical benefit with gemcitabin as first - time therapy for patients with advanced pancreas cancer: a randomized triM[ J]. J Clin Oncol, 1997 , 15(6) :2403.
  • 3Allen AM, Zalupski MM, Robetson JM, et al. Adjuvant therapy in pancreatic cancer: Phase I trial of radiation dose escalation with concurrent full - dose gemcitabine[ J]. Int J Radiat Oncol Biolphys,2004,59 (5) :1461.
  • 4Bussela B, Goethalsa L, Femb M. Respiration- induced movement of the upper abdominal organs : a pifful for the three - dimensional conformal radiationtreatment of pancreatic cancer [ J ]. Radiother Oncol, 2003,68:69.
  • 5Blackstock AW, Cox AD,Tepper IE. Treatment of pancreatic cancer: currentlimitations,future possibilities[ J]. Oncology, 1996,10 (3) :301.
  • 6Schutz RM. Future directions for treatment of human pancreatic carcinoma[ J]. Expert Opin Invest Drug, 1995,4 : 1273.
  • 7Ceha H M, wan Tie - hoven G, Gouma D J , et al . Feasibility and efficacy of high dose conformal radiotherapy for patients with locally advanced pancreatic carcinoma [ J ]. Cancer,2000,89 ( 1 ) : 222.
  • 8赵美红,马静静,郎丰平,王志永.X线立体定向适形放射治疗高龄晚期胃癌二例报告[J].肿瘤防治杂志,2001,8(3):298-298. 被引量：1

同被引文献20

  • 1张红燕,李建萍,庄海花.胰腺癌动脉灌注健择的护理[J].解放军护理杂志,2004,21(6):59-59. 被引量：1
  • 2邰雅宏,王亚东.吉西他滨静脉滴注治疗晚期胰腺癌疗效分析[J].湘南学院学报（自然科学版）,2004,6(4):7-8. 被引量：3
  • 3Freelove R,Walling AD. Pancreatic cancer: diagnos is and man- agement[J]. Am Fam Physician, 2006, 73 (3) : 485-492.
  • 4Katz A , Hanlon A , Hanlon R , et al. Prognostic value of CA19- 9 levels in patients with carcinoma of the pancreas treated with ra- diotherapy[J] . Int J Radiat Oncol Biol Phys, 1998, 41 (2) : 393- 596.
  • 5Loehrer PJ, Powell ME, Cardenes HR, et al. A randomized phase III study of gemcitabine in combination with radiationtherapy ver- sus gemcitabine alone in patients with localized, unresectable pan- creatic cancer: E4201 [ J ]. J Clin Oncol, 2008, 26 (1) : 4506.
  • 6Higgins PD, Sohn JW, Fine RM, et al. Three-dimensional confor- mal pancreas treatment: comparison of four-to six-field techniques [ J ]. Int J Radiat Oncol Biol Phys, 1995,31 ( 3 ) :605- 609.
  • 7Storniolo AM, Enas NH , Brown CA , et al. An investigation new drag treatment program for patients with gemcitabine : results for o- ver 3000 patients with pancreatic carcinoma [ J]. Cancer, 1999, 85 (6) : 1261-1268.
  • 8Wilkowski R, Thoma M, Bruns C, et al. Chemoradiotherapy with gemcitabine and continuous 5-FU in patientswith primary inopera- ble oancreatic cancer[J]. JOP, 2006.7 (4) : 349-360.
  • 9Burris HA, Moore M J, Andersen J, et al. Improvements in sur- vival and clinical benefit with gemcitabin as first-time therapy for patients with advanced pancreas cancer : a randomized trial [ J ]. J Clin Oncol, 1997, 15(6) : 2403.
  • 10Crane CH, Abbruzzese JL, Evans DB, et al. Is the therapeutie index better with gemeitabine-based ehemoradiation than 5-Fu based ehemoradiation in locally advanced pancreatic cancer [ J ]. Int J Radiat oIlcol Biol Phys, 2002, 2(5) : 1299-1300.

引证文献2

二级引证文献4

华北煤炭医学院学报
2009年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部