摘要
目的:了解我院药品不良反应(ADR)发生的规律与特点。方法:收集我院2008年各科室上报的ADR报告208例,有效报告207例,按患者的性别、年龄、给药途径、ADR因果关系评定与程度、ADR类型及临床表现等方面进行统计、分析。结果:207例有效ADR报告中,30～49a患者ADR发生率最高,占38.65%;静脉给药途径ADR发生率最高,占87.92%;抗感染药致ADR发生率最高,占53.62%;最常见的ADR临床表现为皮肤及其附件损害,占59.91%。结论:临床应合理应用抗菌药物和静脉注射药物,以减少ADR的发生。
OBJECTIVE： To analyze the regularity and characteristics of adverse drug reactions （ADR） occurred in our hospital. METHODS： A total of 208 ADR cases （207 cases were valid） reported by clinical departments of our hospital were analyzed statistically in respect of patients＇ age and sex, routes of administration, causal relationship assessment and extent of ADR, ADR types and clinical manifestations,etc. RESULTS： Of the 207 valid ADR cases, 38.65% of them aged between 30 and 49; intravenous route accounted for 87.92% in terms of the incidence rate of ADR; anti - infective drug accounted for 53.62%. The most common clinical manifestations of ADR were the lesions of skin and its appendants, which accounted for 59.91%. CONCLUSION： Antiinfective drugs and intravenously injected drugs should be used rationally to reduce the incidence of ADR.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第26期2058-2060,共3页
China Pharmacy
基金
宁波市医学科技计划项目(2006040)
关键词
药品不良反应
报告
分析
Adverse drug reaction
Report
Analysis
