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终末期肾功能衰竭维持血透患者动脉粥样硬化与血清HGF相关性观察

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摘要 目的探讨终末期肾功能衰竭维持血液透析患者动脉粥样硬化与血清HGF的相关性。方法终末期肾功能衰竭患者100例(观察组)和对照组(30例),测定总胆固醇(TC)、三酰甘油(TG)和高密度脂蛋白(HDL)和血清肝细胞生长因子(HGF)和脂蛋白(LP),用高分辨二维颈动脉超声技术检测颈动脉内-中膜厚度、粥样动脉硬化斑块。结果维持性血液透析患者血清肝细胞生长因子水平较对照组明显升高(P<0.05);血清肝细胞生长因子水平与动脉粥样硬化病变程度呈正相关(P<0.05)。结论血清中的HGF可以作为动脉粥样硬化的预警指标,为临床诊断和治疗提供可靠的理论依据。
作者 黄国武
出处 《中国现代药物应用》 2009年第18期66-67,共2页 Chinese Journal of Modern Drug Application
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