摘要
目的探讨磁共振弥散张量成像（diffusion tensor imaging,DTI）对脊髓损伤的临床诊断价值。方法选择健康志愿者42例作为对照组和脊髓型颈椎病患者64例进行颈椎常规MRI及弥散张量成像,分别测量各组表观弥散系数（ADC）、部分各向异性（FA）值,并显示其弥散张量纤维束（DTT）。结果正常组的平均ADC值为（830.34±215.86）×10^-6mm^-2/s,平均FA值为（536.03±40.00）×10^-3。颈髓慢性损伤患者平均ADC值为（1107.60±47.55）×10^-6mm^-2/s,较正常组升高,有统计学意义（P〈0.01）,平均FA值为（425.91 x±59.48）×10^-3,较正常组下降,有统计学意义（P〈0.01）。结论磁共振弥散张量成像较常规MRI成像能早期显示颈椎病脊髓的损伤,ADC值、FA值、DTT图是检测早期脊髓损伤微观结构的敏感指标。
Objective To investigate MRI diffusion tensor imaging for the clinical diagnosis of cervical spondylotic myelopathy in patients with spinal cord injury. Method Conventional MRI scans of cervical and diffusion tensor imaging were performed in 64 patients with cervical spondylotic myelopathy and 42 cases of healthy volunteers as a healthy control group. Apparent diffusion coefficient （ADC） and fractional anisotropy （FA） were measured, diffusion tensor tracking was showed in each group. Results The average ADC value was （830.34±215.86） × 10^6 mm^2/s and the average FA value was（536.03±40.00） × 10^-3 in control group. The average ADC value in cervical spondylotic myelopathy group was（ 1107.60± 47.55） × 10^6 mm^2/s, which was statistically higher than that in the control group （P^0.01）. The average FA value was（425.91x±59.48） × 10^-3 , which was statistically lower than that in control group significantly（P〈 0.01）. Conclusion MRI diffusion tensor imaging can show the early injury in the spinal cord, which is better than conventional MRI imaging. In cervical spondylotic myelopathy ADC values,FA values and DTT are sensitive indicators of early detection of micro-structure of spinal cord injury.
出处
《实用疼痛学杂志》
2009年第4期265-269,共5页
Pain Clinic Journal
关键词
磁共振
弥散
弥散张量成像
脊髓损伤
Magnetic Resonance
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging, Spinal Cord Injury
