摘要
目的:了解我院2006～2008年临床分离的病原菌群分布及对抗生素耐药性变化趋势,为临床合理选用抗生素提供依据。方法:对临床分离的病原菌进行回顾性分析研究,用ATB系统鉴定菌株及药敏试验。结果:3年间共检出病原菌534株,依次是大肠埃希菌(45.7%)、肺炎克雷伯菌(29.2%)、铜绿假单胞菌(25.1%)。ESBLs的检出率由2006年的23.8%上升到2008年的37.9%。对大肠埃希菌和肺炎克雷伯菌敏感率最高的抗生素是亚胺培南(100%),对铜绿假单胞菌敏感率最高的抗生素是多粘菌素E(92.4%)和阿米卡星(78.6%)。结论:应加强病原菌的监测,关注致病菌分离及耐药性变化情况,合理选用抗生素。
Objective： To study the pathvgen distribution and trends of drug-resistance of bacteria isolated from patients invcer hospital from 2006-2008 and to provide refrence basis for rational use of antibiotic. Methods： ATB system method was used to be identification of bacteria and test drug sensitivity and the re- sults isolated from patients were analtzed. Results： A total of 534 strains of pathogens were detected for three years, the outstanding pathogens were E. coli 45.7%, K. pneamoniae 29.2%, P. atruginosa 25.1%. There was ascending tendency in ESBLs from 2006 to 2008. The Sensitivity nate of E. coli and K. pnecemoniat to IMP was the highest （100%）, the seasitivity nate of P. aeruginosa to COL and to AK was 92.4% and 28.6%. Conclusions： Clinical microbiology department should monitor pathogens cveel and study anti- biotic nesistance of pathogens isolated from patients. Rational use of antibiotic is important .
出处
《新疆医科大学学报》
CAS
2009年第9期1273-1275,共3页
Journal of Xinjiang Medical University
关键词
病原菌
抗生素
耐药性
bacteria
antibiotic
drug-resistance
