摘要
以2-碘苯甲酸和甲基丙烯酸羟乙酯(HEMA)为原料,通过酯化反应制得2-(2’-碘苯甲酰)-氧-甲基丙烯酸乙酯(2-IEMA),并用乳糖内酯与2-氨乙基甲基丙烯酸甲酯盐酸盐反应得到2-乳糖氨乙基甲基丙烯酸甲酯(LA-MA),采用自由基溶液聚合的方法将这两种单体与甲基丙烯酸甲酯(MMA)共聚,合成一系列不同组成的X光显影的三元共聚物P(2-IEMA-LAMA-MMA)(MLIx).利用1H NMR计算该共聚物中三种不同结构单元的摩尔分数比,结果表明其与投料比基本吻合.GPC测得该共聚物的相对分子质量分布均小于1.6.X光显影性测试表明,共聚物具有很好的显影性.
A kind of new radiopaque copolymers synthesized via the free radical polymerization of 2-（2＇-iodobenzoyl）ethyl methacrylate（2-IEMA） with lactobionamidoethyl methacrylate（LAMA） in the presence of methyl methacrylate（MMA）. 2-IEMA was prepared from the esterification of 2-iodobenzoyl chloride with HEMA. LAMA was synthesized from the reaction of lactobionolactone with 2-aminoethyl methacrylate hydrochloride. The structures of the resulting MLIr copolymers were characterized by using FTIR, 1H NMR and GPC analyses. The composition of 2-IEMA, LAMA and MMA in the chains can be calculated by ^1 H NMR spectrum which was found to be in agreement with the feed ratios. GPC analyses presented a nearly symmetrical and unimodal peak with a polydispersity below 1.6. These copolymers indeed showed the radiopacity as evidenced by X ray fluoroscopy.
出处
《北京理工大学学报》
EI
CAS
CSCD
北大核心
2009年第8期732-736,共5页
Transactions of Beijing Institute of Technology
关键词
X光显影聚合物
自由基聚合
含糖聚合物
三元共聚物
radiopaque polymer
free radical polymerization
sugar-containing polymers
copolymer
