摘要
目的了解高脂血症性急性胰腺炎（HL—AP）的临床特点，提高对HL-AP的认识。方法回顾159例急性胰腺炎（AP）患者资料，其中18例HL-AP、141例为其他病因的AP，对两组的年龄、甘油三酯（TG）、血钙（Ca^2＋）、血糖（GLU）、CT严重指数（CTSI）、急性生理和慢性健康评分（APACHEII）及合并糖尿病酮症酸中毒（DKA）的发生率进行比较，并将HL-AP组的TG值与上述指标进行相关分析。结果HL-AP组与对照组相比除Ca^2＋明显下降外，TG、APACHEⅡ评分、CTSI、GLU和合并DKA的发生率均显著性增高（均P〈0．05）。HL-AP组TG值和APACHEⅡ评分、CTSI均呈正相关（均P〈0．05）；TG值和Ca^2＋水平存在直线负相关（r=-0．795，P〈0．01）关系。结论HL-AP临床并不少见，其血清TG水平与HL-AP的病变程度呈正相关，且病情较严重，应重视对HL-AP的早期诊断和治疗。
Objective To study the clinical features of hyperlipidemic acute pancreatitis（HL-AP） and to enhyance the awareness of diagnosis and treatment of HL-AP. Methods To Retrospective analyse 159 cases with acute pancreatitis （ AP）, of which 18 cases of HL-AP（ HL-AP group）, 141 cases of other causes of AP（ non-HL-AP group） , to compare the age, triglyeeride （TG）, calcium （ Ca^2＋ ） levels, blood glucose （ GLU ）, CT severity index （ CTSI）, acute physiology and chronic health evaluation （APACHE Ⅱ ） and the the incidence of combined diabetic ketoacidosis （DKA） in two groups,correlative analysis between TG in HL-AP group and the above-mentioned indicators was carrird out. Results In addition to significantly decreased Ca^2＋ , TG, APACHE Ⅱ score, CTSI points, GLU, and the combined incidence of DKA were significantly increased （ both P 〈 0. 05 ） in HL-AP group when compared with the control group,TG and APACHE Ⅱ score, CTSI score were positively correlated （P 〈 0. 05 ）, TG and the Ca^2＋ was negatively correlated（ r = -0. 795 ,P 〈 0. 01 ）. Conclusion HL-AP is not uncommon, mainly patients are young and middle-aged with positively correlated between serum TG levels and the HL-AP lesions, and the condition is more serious and,we should pay attention to the early diagnosis and treatment of HL-AP, main treatment is non-surgical treatment.
出处
《中国基层医药》
CAS
2009年第9期1552-1553,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
胰腺炎
高脂血症
综合分析
Pancreatitis
Hyperlipidemia
Meta-analysis
