摘要
目的:制备内皮细胞生长因子口服液并观察其对胃溃疡和胃炎的治疗作用.方法:从牛脑中提取内皮细胞生长因子(ECGF),并将其配制成口服液,对72例胃溃疡患者和76例胃炎患者进行分组疗效观察.结果:对胃溃疡的显效率由对照组的51.5%提高到82.1%,治愈率由15.2%提高到43.6%;对胃炎的显效率由对照组的52.6%提高到81.6%,治愈率由18.4%提高到47.4%.结论:说明该制剂对胃溃疡和胃炎有较好的疗效.
OBJECTIVE: To prepare an oral liquid of bovine brain extracts containing endithelial cell growth factor and observe its clinical value in treating gastric ulcer and gastritis.METHODS:Bovine brain extracts was made according to maciag et al. ,3.5g of this extracts were diluted in 1000ml of water,0.4 -0.8mg of heparin were added.72 cases of gastric ulcer and 76 cases of gastritis were divided in groups and participated in the trial.RESULTS:The effective rates of gastric ulcer were 82.1% for oral liquid group and 51.5% for control group,and the cure rates were 43.6% and 15.2% respectively;The effect rate of gastritis was increased from 52.6% for control group to 81.6% for oral liquid group,and the cure rate was from 18.4% to 47. 4%. CONCLUSION: This preparation had a therapeutic effect for gastric ulcer and gastritis.
出处
《中国现代应用药学》
CAS
CSCD
1998年第5期60-62,共3页
Chinese Journal of Modern Applied Pharmacy
关键词
内皮细胞
生长因子
口服液
胃溃疡
胃炎
制备
endothelial cell growth factor, oral liquid, gastric ulcer,gastritis, therapy