期刊文献+

两种基因检测系统在早期乳腺癌中的研究进展

下载PDF
导出
摘要 在早期乳腺癌(ESBC)如淋巴结阴性乳腺癌患者的治疗中,辅助化疗使远处转移和死亡风险降低了约50%。医师根据一些临床病理诊断标准来判断是否ESBC患者需要接受辅助内分泌治疗和/或化疗。目前ESBC的治疗指南规定:大部分淋巴结阴性、受体阳性的ESBC患者应接受辅助化疗和内分泌治疗。
出处 《癌症进展》 2009年第5期510-514,共5页 Oncology Progress
  • 相关文献

参考文献23

  • 1Early Breast Cancer Trialists' Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15 -year survival: An overview of the randomised trials [J]. Lancet, 2005, 365 : 1687.
  • 2Goldhirsch A, Wood WC, Gelber RD, et al. Meeting highlights: Updated international expert consensus on the primary therapy of early breast cancer [ J ]. J Clin Oncol, 2003, 21 : 3357.
  • 3Carlson RW, Brown E, Burstein H J, et al. NCCN task force report: Adjuvant therapy for breast cancer [ J ]. J Natl Compr Cane Netw, 2006, 4 (Suppl 1 ): S1.
  • 4van de Vijver MJ, He YD, van't Veer LJ, et al. A gene -expression signature as a predictor of survival in breast cancer [J]. N Engl J Med, 2002, 347 : 1999.
  • 5Buyse M, Loi S, van't Veer L, et al. Validation and clinical utility of a 70 - gene prognostic signature for women with node -negative breast cancer [ J ]. J Natl Cancer Inst, 2006, 98 : 1183.
  • 6Wang Y, Klijn JG, Zhang Y, et al. Gene - expression profiles to predict distant metastasis of lymph - node - negative primary breast cancer [J]. Lancet, 2005, 365:671.
  • 7Foekens JA, Atkins D, Zhang Y, et al. Multicenter validation of a gene expression - based prognostic signature in lymph node - negative primary breast cancer [ J ]. J Clin Oncol, 2006, 24 : 1665.
  • 8Paik S, Shak S, Tang G, et al. A multigene assay to predict recurrence of tamoxifen - treated, node - negative breast cancer [J]. N Engl J Med, 2004, 351:2817.
  • 9Habel LA, Shak S, Jacobs MK, et al. A population- based study of tumor gene expression and risk of breast cancer death-among lymph node -negative patients [ J ]. Breast Cancer Res, 2006, 8 : R25.
  • 10Loi S, Piccart M, Sotiriou C. The use of gene - expression profiling to better understand the clinical heterogeneity of estrogen receptor positive breast cancers and tamoxifen response [J]. Crit Rev Oneol Hematol, 2007, 61 : 187.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部