期刊文献+

益肝灵联合干扰素治疗慢性乙型肝炎临床分析 被引量:3

下载PDF
导出
摘要 目的:研究益肝灵联合干扰素对慢性乙型病毒性肝炎的治疗作用。方法:经临床诊断为病毒性肝炎(轻、中度)并乙型肝炎病毒复制指标阳性患者68例,随机分为两组,益肝灵加干扰素和单用干扰素组,疗程6个月。结果:联合治疗组肝功能恢复正常较对照组显著,尤以病毒复制指标转阴率差异显著(P<0.05)。结论:益肝灵、干扰素为治疗慢性乙型肝炎的有效药物,两者合用对慢性乙型肝炎的治疗提供了理想的治疗效果,值得推广。
作者 朱长林
出处 《中国社区医师(医学专业)》 2009年第20期172-172,共1页
  • 相关文献

参考文献3

二级参考文献19

  • 1聂青和.慢性乙型肝炎抗病毒治疗进展回顾[J].实用肝脏病杂志,2005,8(3):148-150. 被引量:16
  • 2Mutchnick MG,Lindsay KL,Schiff ER,et al.Thymosin alpha-1 treatment of chronic hepatitis B:results of a phase Ⅲ multicentre,randomized,double-blind and placebo-controlled study[J].J Viral Hepat,1999,6 (5):397 -403.
  • 3Andreone P,Cursaro C,Gramenzi A,et al.In vitro effect of thymosin-alphal and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with chronic hepatitis C[J].J Viral Hepat,2001,8 (3):194-201.
  • 4Zavaglia C,Severini R,Tinelli C,et al.A randomized,controlled study of thymosin-α1 therapy in patients with anti-HBe,HBV-DNA-positive chronic hepatitis B[J].Dig Dis Sci,2000,45 (4):690-696.
  • 5Sugahara S,Ichida T,Yamagiwa S,et al.Thymosin-alpha 1 increases intrahepatic NKT cells and CTLs in patients with chronic hepatitis B[J].Hepatol Res,2002,24 (4):346-354.
  • 6Billich A.Thymosin alpha 1.SciClone Pharmaceuticals[J].Curr Opin Investig Drugs,2002,3 (5):698-707.
  • 7Saruc M,Ozden N,Turkel N,et al.Long-term outcomes of thymosin-alpha 1 and interferon alpha-2b combination therapy in patients with hepatitis Be antigen (HBeAg) negative chronichepatitis B[J].JPharmSci,2003,92 (7):1386-1395.
  • 8You J,Zhuang L,Cheng HY,et al.A randomized,controlled,clinical study of thymosin alpha-1 versus interferon-alpha in patients with chronic hepatitis B lacking HBeAg in China[J].J Chin Med Assoc,2005,68 (2):65 -72.
  • 9Mutchnick MG,Appelman HD,Chung HT,et al.Thymosin treatment of chronic hepatitis B:a place-controlled pilot trial[J].Hepatology.1991,14 (3):409-415.
  • 10Lau GK.Use of immunomodulatory therapy (other than interferon) for the treatment of chronic hepatitis B virus infection[J].J Gastroenterol Hepatol,2000,15 (Suppl):E46-52.

共引文献14039

同被引文献27

引证文献3

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部