摘要
目的探讨肝源性糖尿病胰岛素代谢的临床特点及可能机制。方法对31例肝源性糖尿病与2型糖尿病患者均行OGTT试验,均检测血糖、胰岛素、C肽水平,并计算胰岛素敏感指数、胰岛素抵抗指数。结果肝源性糖尿病患者胰岛素敏感性高于2型糖尿病患者(P<0.05),胰岛素抵抗指数低于2型糖尿病患者(P<0.05)。结论肝源性糖尿病患者血糖水平与肝功能受损程度有一定关系,需降糖治疗时,应首先采用胰岛素治疗。
Objective To investigate the clinical features of liver disease with abnormal insulin metabolism. Methods 31 hepatic diabetes and 25 eases with type 2 diabetics were enrolled in the study and OGTT were measured in all eases. Index of insulin sensitivity and HOMA-IR were used for result analysis. Results Comparing to type 2 diabetics,index of insulin sensitivity was higher in hepatic diabetes. The level of HOMA-IR decreased. Conclusion Heperglyeemia in hepatic diabetes is related to the liver dysfunction. Insulin therapy should be selected first.
出处
《临床消化病杂志》
2009年第5期291-293,共3页
Chinese Journal of Clinical Gastroenterology
