摘要
目的:评价介入化疗栓塞联合射频热疗对晚期胃癌的治疗效果。方法:回顾性分析70例晚期胃癌患者的临床资料,按治疗方法分为介入化疗栓塞联合射频热疗组(A组)与单纯介入化疗栓塞组(B组),观察比较临床症状、影像学、肿瘤标志的变化,以及毒副反应与生存期的差异。结果:术后两组临床症状、影像学和肿瘤标志均有显著改善,且A组优于B组(P<0.05),两组1、2、3年生存期分别为100.0%、90.1%、75.0%和100.0%、81.6%、44.7%,差异有统计学意义,P<0.05。两组均无严重并发症发生,差异无统计学意义,P>0.05。结论:介入栓塞化疗联合射频热疗能显著提高晚期胃癌患者的疗效,延长生存期,安全性高。
OBJECTIVE： To evaluate the efficiency of chemoembolization combined with hyperthermia for advanced gastric cancer. METHODS： The clincal materials of 70 cases of advanced gastric cancer were restrospectively analyzed, and those were divided into Group A, receiving chemoembolization combined with hyperthermia, and Group B, only ehemoembolization. The clineal symptoms, imaging, tumor markers, survival time and toxic and adverse reactions were observed and compared. RESULTS：The clincal symptoms, imaging and tumor markers were all improved significantly in both groups, and the improvement was better in Group A than that in group B （P〈0.05）; the 1 ,2 and 3- year postoperation survial rates in Group A and B were 100.0%, 90. 1%, 75.0%, and 100.0%, 81.6%,44.7% （P〈0.05） respectively, and there was no significant difference in adverse reactions of the two groups （P〉0.05）. CONCLUSION： Chemoemholization combined with hyperthermia can improve significantly the efficiency for advanced gastric cancer, and pro long significantly the survival time of patients, with the high salty.
出处
《中华肿瘤防治杂志》
CAS
2009年第17期1326-1328,共3页
Chinese Journal of Cancer Prevention and Treatment
关键词
回顾性研究
化学疗法
辅助
胃肿瘤/外科学
综合疗法
retrospective studies
chemotherapy, adjuvant
stomach neoplasms/surgery
combined modality therapy
