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高海拔地区老年人Hcy、胰岛素水平与代谢综合征的相关性研究 被引量:3

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摘要 目的探讨青海高海拔地区老年人同型半胱氨酸(Hcy)水平与代谢综合征(MS)的相关性。方法采取随机抽样的方法,对青海省海晏县(平均海拔≥3000m)60岁以上农牧民218人血浆Hcy水平及胰岛素水平进行分析,并与32名正常健康人作比较。结果①青海高原藏族老年人空腹胰岛素水平、体重指数及血浆胆固醇水平明显高于当地汉族老年人,甘油三脂水平明显低于当地汉族老年人(P<0.05)。②MS组血浆Hcy水平、空腹胰岛素水平及服糖2h后胰岛素水平均显著高于正常对照组(P<0.001)。③相关分析显示血浆Hcy与胰岛素水平之间无明显的相关性(P>0.05)。结论①青海高海拔地区不同代谢危险因素对藏、汉族老年人的影响不同,提示针对不同人群干预的重点不同。②高原地区老年MS患者存在明显的高Hcy血症和胰岛素抵抗,它们在青海高原老年MS的发生发展中均起着重要的作用。
出处 《西部医学》 2009年第10期1670-1671,共2页 Medical Journal of West China
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