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利巴韦林气雾剂治疗小儿疱疹性咽峡炎临床观察 被引量:2

Effect of ribavirin aerosol on herpetic angina of children
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摘要 目的临床观察利巴韦林气雾剂治疗小儿疱疹性咽峡炎的疗效。方法共80例临床诊断为疱疹性咽峡炎的患儿,随机分为治疗组和对照组,每组40例,两组病例治疗前性别、年龄、病程及临床症状等无统计学差异。治疗组喷利巴韦林气雾剂,对照组口服双黄连口服液,均连用5d。结果两组用药后,在退热、咽痛、溃疡愈合等方面比较有统计学差异。结论利巴韦林气雾剂治疗小儿疱疹性咽峡炎疗效确切,起效迅速,无毒副作用,可作为治疗疱疹性咽峡炎的首选药。 Objective To study the clinical effect of ribavirin aerosol on herpetic angina of children. Methods A total of 80 children, diagnosed as herpetic angina, were randomly divided into ribavirin aerosol treatment group and control group(n=40) with no statistical difference in gender, age, disease course and clinical symptoms. Patients in treatment group received ribavirin aerosol while those in control group administered oral shuanghuanglian liquid for 5 days, respectively. Results A statistical difference was found in pyretolysis, pharyngodynia, and ulcer healing between the two groups after treatment. Conclusion Ribavirin aerosol has a rapid and significant effect on herpetic angina of children with no side effects and can thus be used as the first line drug for herpetic angina of children.
出处 《军医进修学院学报》 CAS 2009年第5期658-659,共2页 Academic Journal of Pla Postgraduate Medical School
关键词 疱疹性咽峡炎 利巴韦林 病毒 herpangina ribavirin viruses
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  • 1中华人民共和国卫生部药政局.新药(西药)临床研究指导原则汇编.1993.51-53.
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  • 4Rodriguez WJ,Hall CB,Welliver R,et al.Efficacy and safety of aerosolized ribavirin in young children hospitalized with influenza:a double-blind,muticenter,placebo-controlled trial.J Pediatr,1994,125(1):129-135.

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