期刊文献+

两种非洛地平药物经济学分析及对高血压患者左室肥厚的影响 被引量:3

Pharmacoeconomics Analysis of Two Kings of Flodipine and in Treatment of Left Ventricular Hypertrophy in Patients with Essential Hypertension
下载PDF
导出
摘要 目的:评价国产与进口非洛地平药物经济学及两种药物对高血压患者左室肥厚的影响。方法:120例原发性高血压1、2级患者随机分为2组,分别服用国产非洛地平(5mg/次,1次/d)和进口非洛地平(5mg/次,1次/d),每2周随访1次,记录血压情况。结果:1年后,国产非洛地平组治疗费用为540元,进口非洛地平组费用为1404元,降压总有效率分别为63.4%和72.5%,均能明显逆转高血压患者左室肥厚。结论:两组降压总有效率及对左室逆转作用无差异(P>0.05),国产非洛地平的价/效更有优势。 Objective: To compare the clinical efficacy and economic effect of two kings of flodipine in treatment of patients with essential hypertension. Methods: 120 patients with essential hypertension were randomly divided into two groups. Group A were given domestic flodipine 5mg and group B were given imported 5mg everyday, the course of treatment in two groups were one year respectively. The treatment effect and the economic cost effect were evaluated. Results:The blood pressure and ultrasonic monitoring values had no significant difference between the two groups(P〉 0. 05). The total cost of each case was 540 yuan in group A and 1404 yuan in group B, E/C was lower in group A than in the other(P≤0. 05). Conclusion: Domestic flodipine is superior to imported for the treatment left ventrieular hypertrophy in patients with essential hypertension from the viewpoint of economic.
出处 《医学理论与实践》 2009年第10期1165-1167,共3页 The Journal of Medical Theory and Practice
关键词 高血压 非洛地平 药物经济学 左室肥厚 Hypertension Flodipine Pharmacoeconomics Left ventricular hypertrophy
  • 相关文献

参考文献7

  • 1肖惠敏,姜小鹰,陈晓春.影响高血压病人药物治疗依从性的多因素分析[J].高血压杂志,2002,10(3):283-284. 被引量:52
  • 2徐端正.药物经济学及其分析[J].中国新药与临床杂志,2000,19(2):139-142. 被引量:487
  • 3王建生,姜垣,金水高.2002年我国高血压的疾病负担分析[J].中国慢性病预防与控制,2007,15(3):194-196. 被引量:71
  • 4The ALLHAT Officers and coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) [J]. JAMA, 2002,288(23) : 2981-2997.
  • 5Poole-Wilson PA, Lubsen J, Kirwan BA, et al. Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION): randomized controlled trial[J]. Lancet, 2004,364(9437):849-857.
  • 6Nissen SE, Tuzcy EM, Libby P, et al. Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: The CAMELOT study: a randomized controlled trial[J]. JAMA, 2004, 292(18): 2217-2226.
  • 7Terpstra WL, May JF, Smit AJ,et al. Long-term effects of amlodipine and lisinopril on left ventricular mass and diastolic function in elderly, previously untreated hypertensive patients: the ELVERA trial[J]. J Hypertens, 2001, 19 : 303-309.

二级参考文献8

共引文献607

同被引文献42

引证文献3

二级引证文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部