摘要
目的探讨手足口病患儿血清心肌酶谱及心肌肌钙蛋白1（cTn1）对心肌功能损伤的临床意义。方法收集南宁地区2008-04—2009-05手足口病（HFMD）患儿83例，用日本生产的Automatic Analyzer HITACHI7600-120型检测仪检测心肌酶谱（AST、LDH、CK及CK—MB）和美国亚培生产的AbbottAxSYM系统全自动化学发光免疫分析系统检测cTn1。结果83例HFMD患儿的血清心肌酶谱AST、LDH、CK、CK．MB及cTn1检测结果均明显高于正常对照组（P〈O．05或P〈0．01）。结论联合检测HFMD患儿血清心肌酶谱（特别是CK-MB）及cTn1在早期诊断HFMD及了解该病的损伤情况有着重要的临床意义。
Objective To study the clinical significance of serum myocardial enzymogram and troponin 1 for juding the myocardial injury of hand foot mouth disease （HFMD） children. Methods The myocardial enzymogram （AST, LDH, CK and CK-MB） in serum of 83 HFMD children collected in Nanning area from April 2008 to June 2009 were detected by Automatic Analyzer HITACHI 7600 120, and the cardiac troponin 1 （cTnl） in serum of 83 FHMD children were detected by Abbott AxSYM chemilumin-escent immunoassay. Results Compared with healthy volunteers AST, LDH, CK, CK-MB and cTnl in serum of 83 HFMD children increased significantly（ P 〈 0. 05 or P 〈 0. 01）. Conclusion Combined detection of serum cTnl and myocardial enzymogram especially （CK-MB） have the important clinical meaning for the early diagnosing HFMD and judging myocardial injury.
出处
《中国临床新医学》
2009年第9期938-940,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
