摘要
目的:探讨白细胞介素-1β(IL-1β)与病毒性脑炎的关系。方法:采用放射免疫分析(RIA)法检测54例病毒性脑炎患儿血清及脑脊液中白细胞介素-1β(IL-1β)含量。结果:急性期各型患儿血清及脑脊液中IL-1β即显著增高,其增高程度与病情严重程度密切相关;恢复期血清中IL-1β降至正常,而重型患儿脑脊液中的IL-1β含量仍显著高于对照组。结论:IL-1β参与了病毒性病理生理过程,其含量的测定对病情严重程度的判断有重要参考价值。
Objective： To study the relationship between interlukin-1β （IL-1β） and acute virus encephalitis in children. Methods： The content of IL-1β in serum and cerebrospinal fluid （CSF） from 54 eases of patients with acute virus encephalitis was determined with radioimmtmoassay （RIA）. Results：In the acute phase,the content of IL-1β in serum and CSF was higher than that of the control, and it was consistent with the severity of the disease. In the convalescence phase, the content of IL-1β decreased to normal level in serum, but keep higher level in CSF of severe patients. Conclusion：IL-1β takes part in the pathophysiology process of acute virus enoephalitis, which is helpful for judging the disease＇s condition.
出处
《四川省卫生管理干部学院学报》
2009年第2期106-108,共3页
Journal of Sichuan Continuing Education College of Medical Sciences
关键词
病毒性脑炎
白细胞介素-1Β
血清
脑脊液
Acute Vires Encephalitis
Interlukin-1β
Serum
Cerebrospinal Fluid.
