摘要
蛋白质组学从整体上,全面、动态、定量地分析正常及肿瘤标本中蛋白质种类和数量的改变,有助于阐明肿瘤相关蛋白质间的调控网络。卵巢癌是女性生殖器官恶性肿瘤中首位的致死性疾病,但卵巢位置隐匿,卵巢癌早期往往没有特异性症状,而现有的卵巢癌肿瘤标志物用于卵巢癌诊断价值有限,导致70%-75%的卵巢癌确诊时已是晚期,5年存活率低于30%,严重危害妇女健康。而蛋白质组学对上皮性卵巢癌具有广阔的应用前景,有助于卵巢癌的诊断、治疗等。
Proteomics can analyze the changes of type and quantity of protein from normal and tumor specimens with overall, comprehensive, dynamic and quantitative. It helps to illuminate the regulatory net- works of tumor-associated protein. Ovarian cancer is a malignant tumor of female genital mutilation in the first of the fatal disease. The location of ovarian is occult. Ovarian cancer symptoms are often not specific, Further- more,because the existing ovarian cancer tumor markers for its diagnosis is limited,70% -75% of diaguosed ovarian cancer was in its advanced stage. 5-year survival rate is less than 30%, seriously endangering women＇ s health. Proteomies of epithelial ovarian cancer has broad application prospects and helpful to ovarian cancer diagnosis and treatment.
出处
《医学综述》
2009年第19期2951-2953,共3页
Medical Recapitulate
