摘要
目的探讨急性心肌梗死(AMI)合并代谢综合征患者的危险因素及冠状动脉(冠脉)病变特点。方法将确诊为AMI的312例患者按有无合并代谢综合征分为AMI合并代谢综合征组和非代谢综合征组,分别对其危险因素和冠脉病变特点进行分析。结果AMI合并代谢综合征组和非代谢综合征组患者的性别构成、是否吸烟、收缩压水平、空腹血糖和餐后2h血糖水平、三酰甘油水平、高密度脂蛋白胆固醇及纤维蛋白原水平比较,差异有统计学意义(P<O.05);代谢综合征组患者冠状动脉造影显示病变血管为1支病变、2支病变和多支病变的例数分别为41、32和36例,非代谢综合征组患者分别为107、57和39例,两组间差异有统计学意义(u=108.00,P<0.05)。MAI合并代谢综合征1支血管病变、2支血管病变和多支血管病变患者的危险因素的数量间差异有统计学意义(χ2=26.71,P<0.05)。结论代谢综合征通过促使动脉粥样硬化及血栓形成,导致心血管意外的发生增加,积极控制可能的危险因素在预防AMI发生中具有重要作用。
Objective To study the risk factors of patients with acute myocardial infarction （AMI） complicated by metabolic syndrome （MS） and the features of the patients＇ coronary artery lesions. Methods Totally 312 diagnosed AMI patients were divided as MS group and non - MS group. Then the risk factors and coronary artery features of the patients were analyzed respectively. Results There were significant differences between MS group and non - MS group in gender, smoking, and the levels of systolic blood pressure, fasting blood glucose, 2 - h postprandial blood glucose, triglyceride, high density lipoprotein - cholesterol and fibrinogen （ P 〈 0. 05 ）. Coronary angiograph showed that the number of patients who had lesions of 1 coronary branch, 2 and several coronary branches in MS group were 41, 32 and 36 respectively, with a significant difference as com- pared with 107, 57 and 39 in non - MS group （ u = 108.00, P 〈0. 05 ）. And there were significant differences in the number of risk factors among patients who had MAI complicated by lesions of 1 coronary branch, 2 and several coronary branches （χ^2 = 26. 71, P 〈 0. 05 ）. Conclusion Metabolic syndrome leads to increase of cardiovascular accidents by promoting coronary atherosclerosis and thrombosis. So it is of important role to actively control the possible risk factors in prevention of AMI.
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第19期1759-1761,共3页
Chinese General Practice
基金
上海市卫生局基金资助项目(044018)
关键词
代谢综合征
急性心肌梗死
危险因素
冠状动脉狭窄
Metabolic syndrome
Acute myocardial infarction
Risk factor
Ceronary stenosis
