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化学发光免疫分析测定胰岛素及C肽在2型糖尿病诊断中的临床应用 被引量:19

Clinical Significance of Detection of Insulin and C Peptide in Type 2 Diabetic Patients by Chemiluminescence Immunoassay
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摘要 应用化学发光免疫分析测定50例2型糖尿病患者及30名正常人血清胰岛素和C肽含量并对测定结果进行分析,了解糖尿病患者糖代谢和胰岛β细胞的功能。结果显示,2型糖尿病患者空腹胰岛素和C肽高于正常人(P<0.05),餐后1h对照组出现峰值,餐后2h糖尿病组达到高峰,餐后3h仍不能恢复至正常水平。结论:化学发光免疫分析检测胰岛素及C肽可用于临床,帮助糖尿病分型,判断病情严重程度及指导治疗。 To explore the clinical significance of insulin and C peptide in type 2 diabetic patients,the serum in- sulin and C peptide levels in 50 type 2 diabetics patients and 30 health controls were determined by chemilumi- nescence immunoassay. The results showed that the serum levels of insulin and C peptide in patients were signif- icantly higher than that of healthy controls (P 〈 0.05). The peak level of blood sugar appeared at 1 hour after meals in healthy controls,while in patients appeared at 2 hours and didn' t return to normal at 3 hours. The ser- um insulin and C peptide levels could be used to determine the function of islet 13 cells and to guide clinical treatment.
出处 《标记免疫分析与临床》 CAS 2009年第5期283-285,共3页 Labeled Immunoassays and Clinical Medicine
关键词 2型糖尿病 胰岛素 C肽 化学发光测定 Type 2 diabetics Insulin C Peptide Chemiluminescent immunoassay
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