摘要
目的:建立应用薄层色谱法、高效液相色谱法和红外光谱法检测常见中成药和保健食品中非法添加的西药。方法:运用薄层色谱法快速初筛,高效液相色谱-二极管阵列初步鉴定,红外光谱法定性鉴定的色谱光谱综合运用技术。结果:建立的方法能够鉴别出添加的格列苯脲、格列齐特、盐酸芬氟拉明、酚酞、盐酸二甲双胍、盐酸西布曲明和枸橼酸西地那非等西药成分。结论:本方法准确可靠,简便易行,易于推广。
Objective：To develop a method for identification of added illegally medicine in Chinese traditional medicne and herbal dietary supplement using spectrometry and chromatography. Method： TLC, HPLC - DAD and IR were adopted. Results： Glibenclamide, gliclazide, fenfluramine hydrochloride, phenolphthalein, mefformin hydro- chloride, sibutramine hydroehloride, sildenafil citrate could be identified by this method. Conclusion：The method is precise, reliable, simple, rapid and can be used universally.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2009年第10期1677-1680,共4页
Chinese Journal of Pharmaceutical Analysis
基金
2007年上海市食品药品监督管理局系统立项研究课题
