摘要
为了提取生物组织的色散信息,提出了一种基于Fourier变换以及多项式拟合的方法.该方法通过对光学相干层析术的干涉包络进行Fourier变换,再将得到的相位谱进行多项式拟合以实现色散信息的提取.通过数值模拟及相关实验验证了该方法的可行性.本文的分析结果不但有助于实现动态的色散补偿,而且可以用于区分不同的生物组织,以及同一生物组织的不同生理状态.
The dispersion signal in optical coherence tomography （OCT） carries the information about the structure and function of bio-tissues. In order to extract the information about the dispersion, a method based on the Fourier transform and the polynomial fit was presented. The interferogram envelope in OCT was Fourier transformed to the frequency domain, and then the second order dispersion information was obtained by performing a polynomial fit to the phase spectrum. Theoretical simulation and experimental data validated the method. The obtained results in this work not only could be used for the dynamical dispersion compensation, but also provide a way to characterize different tissues,and different physiological conditions.
出处
《光子学报》
EI
CAS
CSCD
北大核心
2009年第10期2598-2602,共5页
Acta Photonica Sinica
基金
国家教育部博士点基金(200802880013)
江苏省自然科学基金(BK2008412)
江苏省六大人才项目基金(06-B-041)
江苏省高校青蓝工程基金
“江苏省‘333高层次人才培养工程’专项资助”
南京理工大学青年学者基金(Njust200302)
苏州大学重点实验室基金(KJS01002)等资助
