摘要
In the present study, hemodynamics of the internal carotid artery-posterior communicating artery （ICA-PComA） was numerically modeled with CFD approach. The steady and pulsating blood flow in the ICA-PComA was simulated. The main concern was placed on the influence of aneurysm geometry on the local hemodynamics by changing the sac diameter and Aspect Ratio （AR） of the aneurysm. The numerical results show the significantly weakened Wall Shear Stress （WSS） and the intensified wall pressure in the aneurysm as AR is increased. Two factors, i.e., low WSS and high pressure of the aneurysm, may play important roles in the fragile change of the aneurysm and the final rupture. The distributions of Time-Averaged WSS （TAWSS）, Oscillatory Shear Index （OSI） and spatial WSS Gradients （WSSG）） were determined and discussed in view of their influences on the evolution of ICA-PComA aneurysm.
In the present study, hemodynamics of the internal carotid artery-posterior communicating artery （ICA-PComA） was numerically modeled with CFD approach. The steady and pulsating blood flow in the ICA-PComA was simulated. The main concern was placed on the influence of aneurysm geometry on the local hemodynamics by changing the sac diameter and Aspect Ratio （AR） of the aneurysm. The numerical results show the significantly weakened Wall Shear Stress （WSS） and the intensified wall pressure in the aneurysm as AR is increased. Two factors, i.e., low WSS and high pressure of the aneurysm, may play important roles in the fragile change of the aneurysm and the final rupture. The distributions of Time-Averaged WSS （TAWSS）, Oscillatory Shear Index （OSI） and spatial WSS Gradients （WSSG）） were determined and discussed in view of their influences on the evolution of ICA-PComA aneurysm.
基金
supported by the Science and Technology Commission of Shanghai Municipality (Grant Nos.08JC1411200,064307056)
